CBG Medical Benefits.

What is CBG? Lately we have heard a lot about CBD medical benefits. CBG is also known as cannabigerol and is the non-acidic form of cannabigerolic acid or CBG-A. CBG-A could be considered the mother of cannabinoids because it is ultimately converted to THC, CBD and others. In this article we won’t be talking much about how cannabinoids are made. Most cannabis strains contain less than 1% CBG. Even though it occurs in such small amounts there is developing interest in CBG medical benefits.

What is CBG used for?

Animal studies are the source of research looking at CBG medical benefits. As with CBD and THC much research is needed to fully understand both the medical benefits of cannabis as well as possible risks.

Initial research has been done in the following areas.

  • Analgesic: for pain
  • Antibacterial: to combat bacterial growth
  • Anti-convulsive: to treat seizures and convulsions
  • Anti-inflammatory: to reduce inflammation
  • Anti-insomnia: to improve sleep
  • Anti-proliferative: to inhibits growth of cancer cells
  • Antidepressant: to boost mood
  • Bone stimulant: to encourage bone growth
  • Appetite stimulant: to increase appetite
  • Brain cell stimulant: to encourage growth of brain cells

How does CBG Work?

CBG interacts with the endocannabinoid system (ECS) in our body. The ECS consists of CB1 and CB2 receptors.

Anandamide (AEA) and 2-arachidonoylglycerol (2-AG) are endocannabinoids. These are natural cannabinoids that our body produces.

These, endocannabinoids bind with CB1 and CB2 receptors and regulate physiological functions.

Research shows that CBG binds with CB2 receptors. In high doses, it could block other compounds from binding with CB1 receptors. Studies that looked at CBG interactions with CB2 receptors showed some promising results.

Other activities

CBG has a variety of other activities, such as being a Serotonin 5-HT1A Antagonist and an Adrenergic Receptor Agonist but for the most part, these seem to either not be unique, or not be potent enough to be relevant.

Is CBG Legal?

Like CBD, CBG is legal in Canada. You should be cautious about where you buy any of your cannabis products. There are many illegal sources of cannabis online. We recommend you only purchase cannabis products from legal sources where quality checks are in place to ensure your product is regulated for harmful mould, fungus and pesticides.

CBG oil may be much more expensive than CBD oil. This is because CBG is an expensive cannabinoid to produce. Producing small amounts of CBG takes lots of plant material.

Although CBG is non-intoxicating and legal, I’m not ready to start recommending specific strains that might be a bit higher than others in CBG. There are other factors to consider for our clients including cost, dosage form and availability that for me, make CBG a secondary consideration at this time. We will see what the future brings.”

Mark Churman, M.D., C.C.F.P.

The Bottom Line

Although much more research is required, it seems that CBG has the potential to treat some medical conditions. Some of its actions are not unique and medications do exist that can do some of the same things that CBG can do.

Still, there may be some unique qualities to find in CBG that will provide new therapeutic benefits. We will need to watch and see.

Stay tuned with Weedwell™ as we follow developing research around this cannabinoid. We will continue to ask “What is CBG” and share our findings with you.

Be Well.

Mark Churman, M.D., C.C.F.P.


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